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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOLC1 All Species: 16.67
Human Site: S388 Identified Species: 28.21
UniProt: Q14978 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14978 NP_004732.2 699 73603 S388 A G T T K N S S N K P A V T T
Chimpanzee Pan troglodytes XP_001171017 700 73581 S389 A G T T K N S S N K P A V T T
Rhesus Macaque Macaca mulatta XP_001112196 701 73703 S389 A G T T K N S S N K P A V T I
Dog Lupus familis XP_851848 704 74723 C395 G T T K N L S C R P V T T P K
Cat Felis silvestris
Mouse Mus musculus O08784 1320 134983 P836 S D S D T E M P S A Q A I K S
Rat Rattus norvegicus P41777 704 73545 S398 S A T K S P L S K P A V T P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511079 669 69188 A342 D E A P A K P A P A T K A K K
Chicken Gallus gallus XP_421630 694 72200 T371 Q P V I K N T T K P A K A A A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689627 1001 102013 K593 P A T T P V S K P T P A K P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730693 686 70584 A346 T P A K A I P A K K A A S S D
Honey Bee Apis mellifera XP_001120943 685 75016 E364 S S S E D S S E E E P Q V K K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796224 791 84162 S456 S S D S E S D S D V P A P S K
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001168628 517 55362 K221 D D H K L D G K K K K K N K K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32583 406 40997 S110 S G S S S S S S S S S D E S S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 94.2 81.5 N.A. 24.9 74.1 N.A. 50.7 43.6 N.A. 36.6 N.A. 27.3 22 N.A. 34.5
Protein Similarity: 100 98.8 95.5 85.6 N.A. 36.7 81.2 N.A. 60.3 57.5 N.A. 47.5 N.A. 42.3 42.9 N.A. 47.9
P-Site Identity: 100 100 93.3 13.3 N.A. 6.6 13.3 N.A. 0 13.3 N.A. 40 N.A. 13.3 20 N.A. 20
P-Site Similarity: 100 100 93.3 13.3 N.A. 40 20 N.A. 6.6 26.6 N.A. 40 N.A. 26.6 46.6 N.A. 60
Percent
Protein Identity: N.A. 23.6 N.A. N.A. 25.1 N.A.
Protein Similarity: N.A. 40.9 N.A. N.A. 39.4 N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. 20 N.A.
P-Site Similarity: N.A. 13.3 N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 15 15 0 15 0 0 15 0 15 22 50 15 8 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 15 15 8 8 8 8 8 0 8 0 0 8 0 0 8 % D
% Glu: 0 8 0 8 8 8 0 8 8 8 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 29 0 0 0 0 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 8 0 0 0 0 0 0 8 0 8 % I
% Lys: 0 0 0 29 29 8 0 15 29 36 8 22 8 29 43 % K
% Leu: 0 0 0 0 8 8 8 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 29 0 0 22 0 0 0 8 0 0 % N
% Pro: 8 15 0 8 8 8 15 8 15 22 43 0 8 22 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % R
% Ser: 36 15 22 15 15 22 50 43 15 8 8 0 8 22 15 % S
% Thr: 8 8 43 29 8 0 8 8 0 8 8 8 15 22 22 % T
% Val: 0 0 8 0 0 8 0 0 0 8 8 8 29 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _